The Journal

The unfiltered version

The comparison is the facts. The Journal is the rest of it — what it's like to be dismissed for years, how to advocate for yourself, and how to recognize care that actually listens. Written by the women behind Selene.

The risk that doesn't stay in the pelvis

Twenty-five years of records from nearly three million women found a 46% higher risk of type 2 diabetes with endometriosis — and the association was strongest in the women least likely to be screened for it.

The fourfold number

More than 413,000 women, a fourfold higher risk of atherosclerotic heart disease — and it did not go away when researchers adjusted for weight. Why "lose weight and come back" is not a cardiovascular plan.

The conversation that should happen on day one

The first international consensus guidance on GLP-1s across contraception, conceiving, pregnancy and breastfeeding landed in late July. What it says, what it admits nobody knows, and the counselling you should be getting.

The pill on the menu

There is now an FDA-approved GLP-1 you swallow, and it has reached the telehealth dropdowns. What a tablet genuinely solves, what it doesn't, and why the format matters less than who is prescribing it.

The comment period closed

The FDA's 503B bulks-list proposal shut to public comment on July 30. Nothing is final — but if your prescription is compounded, here are the five questions worth asking your provider this month.

The muscle nobody warns you to protect

Menopause already speeds bone loss — and a GLP-1 can quietly take muscle and bone with the weight. What the 2026 experts say, and the questions to ask before you start.

One in six

GLP-1 use among women with PMOS (PCOS) jumped more than sevenfold in four years. What's really driving it, what the evidence supports, and why semaglutide is still the better-studied choice.

The clue in the peritoneal fluid

Women with endometriosis were found to have lower GLP-1 levels where the disease lives. An intriguing clue — and a long way from a treatment. The early science, held carefully.

The warning nobody reads aloud

How a GLP-1 can quietly change the way your birth control works — and restart a fertility no one warned you about. The line from the paperwork that actually matters.

What endo patients told a survey

In 2026 researchers finally asked women with endometriosis what GLP-1s did for them. What the early evidence shows, what it can't yet — and why we keep our voice careful.

The menopause nobody prepared you for

The weight that arrives in your forties isn't a discipline failure — it's a hormone story. What the newest research says about GLP-1s in perimenopause and menopause.

Eleven years to a diagnosis

Why endometriosis takes so long to name, what a decade of "it's just a bad period" does to a person — and how to advocate for the care you deserve.

You are not a willpower problem

Ten years of diets that were supposed to fix you, the insulin piece no one mentions, and how to find a provider who treats PMOS (PCOS) as the metabolic condition it is.

Occasional notes from the team. We write about what we're learning, what we're still figuring out, and the small, unglamorous things that help — being dismissed, advocating for yourself, and recognizing good care when you finally find it. Check back, or follow along from the about page.

These posts are general information from the women who write Selene. They are not medical advice, not recommendations, and not promises of any result — everyone's experience is different and results vary. Selene is editorial; we don't prescribe, sell, or dispense anything. GLP-1 medications are not FDA-approved specifically for PMOS (PCOS) and are not a treatment for endometriosis. Always talk to a licensed clinician about your own care.