Methodology
How we rate
One published standard, applied the same way to every provider. No numbers, no leaderboard, no paid placement.
Selene editorial · Reviewed periodically
Most GLP-1 comparison sites rank providers by price. That's the wrong question for women with PMOS (PCOS) or endometriosis, where the difference between providers is whether anyone actually understands the hormones underneath your weight. So instead of a price leaderboard — or any leaderboard — Selene publishes a Care Standard and reads every provider against it the same way, rating each part with simple stars rather than scores.
An important medical note. GLP-1 medications have real, published evidence behind their use in PMOS (PCOS), which is closely linked to insulin resistance. GLP-1 medications are
not a treatment for endometriosis. Where endometriosis appears in our standard, it measures only whether a provider understands your endo and hormonal context when managing care — never whether a GLP-1 "treats" it. Nothing here is medical advice.
The seven dimensions
Each provider is read on these. The first two are tuned to this audience and lead every card as the PMOS (PCOS) fit and Endo-aware read; the rest are universal markers of good GLP-1 care.
- PMOS (PCOS) & insulin-resistance literacy (PMOS (PCOS) fit). Does the provider treat PMOS (PCOS) as the metabolic, insulin-driven condition it is — and use that to guide GLP-1 care — rather than treating weight in isolation?
- Whole-woman hormonal context (Endo-aware). Does the provider take your full hormonal and gynecologic history — including endometriosis — into account, screen for contraindications, and avoid dismissing overlapping symptoms? (This reads understanding, not treatment of endo.)
- Individualized, compounded dosing. Is the dose titrated to your response, rather than a flat, one-size tier?
- Reachable clinical support. Can you reach a real clinician quickly when side effects or questions come up?
- Maintenance & off-ramp plan. Is there a real plan for staying well and tapering — not just selling monthly vials?
- Honest, transparent billing. Is pricing clear and all-in, without surprise auto-renew, hidden consult fees, or cancellation traps?
- Community & accountability. Is there ongoing peer support or coaching to help results last?
The ratings
We deliberately don't publish a single number — a precise "score" implies a precision no rubric really has, and it turns honest "these three are all strong" results into a false race. So we keep it simple. The two dimensions this audience cares about most each get a single star at the top of every card:
- a teal star for PMOS (PCOS) fit · a gold star for Endo-aware care
- full = clearly offered · half = partial or unclear · empty = not offered
The five remaining care basics — dosing, support, maintenance, billing, and community — get a simple check: ticked when a provider offers it, dashed when it doesn't. That way you see at a glance how a provider does on the two hardest-to-find things, with the basics right below. Price is recorded and shown, but price is never part of the rating.
Tiers
For the comparison, providers are grouped by overall strength across the whole standard and listed alphabetically within each group. The tiers are a plain-language summary, not a ranking — nothing is curved or weighted:
- Excellent — strong across the whole standard.
- Strong — genuinely good, with real gaps.
- Fair — covers the basics.
- Limited — thin on the dimensions that matter most here.
How we keep it honest
- No pay-to-rank. We accept no payment, commission, or advertising from any provider. Ever.
- Alphabetical within tiers. No "editor's choice," no preferential row, no provider highlighted.
- Publicly verifiable. Ratings reflect what a provider publishes. Where a condition is only partly addressed, it gets a half star, never a full one.
- We don't flatter anyone. No provider is full on every mark, and the cheapest is rarely the best. We leave the read as it is.
Compounded medications
Most providers here dispense compounded semaglutide or tirzepatide. Compounded medications are prepared by licensed pharmacies and are not FDA-approved or reviewed by the FDA for safety, effectiveness, or quality. Where a provider uses a 503A pharmacy — which can prepare individualized formulations — we note it as a badge. A 503A badge describes individualized compounding; it is not a claim that 503A is safer than 503B.
How often we update
We re-verify pricing and offerings periodically. Providers launch, change, and fold; if a provider's site is unreachable during a refresh, we keep the prior read and note it.
See the comparison →